MACROPHAGE COLONY-STIMULATING FACTOR AND ITS ROLE IN THE TUMOR MICROENVIRONMENT: NOVEL THERAPEUTIC AVENUES AND MECHANISTIC INSIGHTS

Macrophage colony-stimulating factor and its role in the tumor microenvironment: novel therapeutic avenues and mechanistic insights

The tumor microenvironment is a complex ecosystem where various cellular and molecular interactions shape the course of cancer progression.Macrophage colony-stimulating factor (M-CSF) plays a pivotal role in this context.This study delves into the biological properties and functions of M-CSF in regulating tumor-associated macrophages (TAMs) and its

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PARTICIPATION, CIVIL SOCIETY AND SOCIAL WORK PRACTICE

In 1994 South Africa became a democracy with Champagne Saucer a government elected by the people for the people.Citizens taking control of their own lives is a general goal of a democracy.The Constitution (RSA, 1996), the Reconstruction and Development Programme (ANC, 1994) and subsequent policy documents all advocate the importance of participatio

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Lower diastolic blood pressure in healthy subjects with vitamin K deficiency: a preliminary cross-sectional study

Introduction.There is a growing body of evidence for the role of vitamin K in cardiovascular health.As a cofactor of carboxylation of the matrix Gla protein it prevents arterial calcification.However, the data on the relationship between vitamin K status and the blood pressure are scarce, and particularly so in persons without the burden of cardi

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Auricular Hematoma in Athletes: Treatment and Risks of Neglect

Introduction: Auricular hematoma is most often caused by direct blunt trauma to the outer ear and is frequently seen in individuals who engage in full-contact sports such as boxing, wrestling, and rugby.This condition occurs when blood accumulates between the cartilage and skin, resulting in pressure that compresses the perichondrium, leading to is

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